Table of Contents
Introduction
Originating from South Korea—a global leader in beauty trends—Rejuran leverages salmon DNA-derived polynucleotides (PDRN) to rejuvenate skin from within.
This article explores everything you need to know about Rejuran, including its variants like Rejuran Healer, Rejuran Skin Booster, and specialized treatments such as Rejuran Eye Injection, while addressing how to integrate these solutions into your skincare regimen.
What is Rejuran?
Rejuran is a non-invasive skin rejuvenation treatment that uses polynucleotides (PN) or polydeoxyribonucleotide (PDRN), derived from salmon sperm DNA.
These molecules are 98% compatible with human DNA, making them highly effective in stimulating collagen production, repairing damaged tissue, and improving skin elasticity and hydration .

Key Components
PDRN/PN: Fragments of salmon DNA that trigger cellular repair and collagen synthesis .
Hyaluronic Acid (HA): Found in some formulations (e.g., Rejuran HB), it enhances hydration and plumps the skin .
Amino Acids and Antioxidants: Added in advanced variants like Rejuran Skin Booster to brighten skin and combat free radicals .
How It Works
Rejuran’s mechanism involves:
1. Collagen Stimulation: PDRN activates fibroblasts, the cells responsible for collagen and elastin production, improving skin firmness .
2. Anti-Inflammatory Action: Reduces redness and irritation, making it suitable for sensitive or acne-prone skin .
3. Deep Hydration: Enhances moisture retention for a plumper, dewier complexion .
Types of Rejuran Treatments
Rejuran offers tailored solutions for diverse skin concerns:
Rejuran Healer
Primary Use: Anti-aging, scar reduction, and overall skin regeneration.
Benefits: – Reduces fine lines, wrinkles, and acne scars .
Improves skin texture and elasticity .
Enhances barrier function for sensitive skin .
Procedure: Administered via microinjections into the dermis, typically requiring 3–4 sessions spaced 2–4 weeks apart .
Rejuran Skin Booster
Primary Use: Hydration and radiance enhancement.
Key Features:
Combines PDRN with hyaluronic acid and vitamins (e.g., Vitamin C) for brightening . Non-invasive delivery via devices like TargetCool冰晶无针水光 (ice-crystal, needle-free technology) .
Ideal For: Dry, dull, or uneven skin tones .
Rejuran I (Eye)
Primary Use: Targeting under-eye concerns like dark circles, puffiness, and crow’s feet. Benefits: – Thickens thin under-eye skin to reduce visibility of blood vessels .
Boosts collagen to smooth wrinkles and tighten sagging skin .
Procedure: Precise injections with fine needles; results visible within 2–4 weeks .
Rejuran HB
Hybrid Formula: Combines PDRN with hyaluronic acid for dual action—repair + hydration .
Best For: Patients seeking both anti-aging and plumping effects .
The Rejuran Procedure: What to Expect

Step-by-Step Process
1. Consultation: A dermatologist assesses skin type and goals .
2. Preparation: Numbing cream is applied to minimize discomfort .
3. Injection: Manual Technique: Fine needles (30G–32G) deliver Rejuran to targeted areas . – Microneedling: For broader coverage, especially in scarred or textured regions .
Rejuran vs. Skinboosters
4. Aftercare: Mild redness or swelling subsides within 24–48 hours. Patients avoid sun exposure and strenuous activities for 1–2 days .
Results Timeline
Immediate Effects: Brighter, hydrated skin . Long-Term Benefits: Collagen remodeling peaks at 4–6 weeks, with optimal results after 3–4 sessions .
Rejuran vs. Other Treatments
Skinboosters: Focus on hydration via hyaluronic acid injections (e.g., Teosyal Redensity I). Less effective for collagen repair .
Rejuran: Superior for anti-aging and tissue regeneration due to PDRN .
Rejuran vs. Profhilo
Profhilo: Uses stabilized HA for bio remodelling. Better for sagging skin but lacks PDRN’s reparative benefits .
Rejuran: Ideal for damaged or aging skin needing cellular repair .
Rejuran vs. Dermal Fillers
Fillers: Add volume to specific areas (e.g., cheeks).
Rejuran: Improves overall skin quality without altering facial structure .
Rejuran in K-Beauty Trends (2025)
Rejuran aligns with 2025’s top Korean beauty innovations:
1. PDRN Dominance: Salmon DNA treatments are hailed for their anti-aging efficacy, with products like VT Cosmetics PDRN Essence gaining popularity .
2. Non-Invasive Focus: Demand for “no downtime” procedures drives Rejuran’s adoption .
3. Combination Therapies: Rejuran is paired with lasers or RF devices for enhanced results .
Safety, Side Effects, and Considerations
Side Effects: Mild redness, swelling, or bruising (resolves in 2–3 days) .
Contraindications: Avoid if allergic to seafood or salmon DNA .
Cost: Varies by region: – Singapore: $300–$800 per session . – Vietnam: $380–$480 for Rejuran Eye .
Where to Buy Rejuran Products
1. Clinics: Accredited providers like SOL Aesthetics (Singapore) and SIAN Clinic (Vietnam) offer authentic treatments .
2. Online Suppliers: Platforms like Maylips supply Rejuran to licensed professionals .
- REJURAN Turnover Ampoule for variety of skin concerns, such as fine lines, loss of firmness, and uneven skin tone.
- VT COSMETICS CICA Reedle Shot 300, Advanced Night Exosome, Microneedling Serum Product Benefits Blackheads Treatment,Whiteheads Treatment,Exfoliating,Blemishes Treatment,Brightening
- VT COSMETICS PDRN 100 Essence, Intensive Glow Serum, Vegan PDRN This PDRN essence is uniquely sourced from Korean ginseng, providing a distinctive ingredient choice, rather than the commonly used fish derivatives.
FAQs
Q: How long do Rejuran results last?
A: 6–12 months, with maintenance sessions recommended every 4–6 months .
Q: Can Rejuran treat acne scars?
A: Yes. Its collagen-boosting action smooths atrophic scars over 3–4 sessions .
Q: Is Rejuran vegan-friendly?
A: No—it contains salmon-derived ingredients .
Conclusion
Rejuran represents a paradigm shift in skincare, offering science-backed solutions for aging, damage, and dehydration.
Whether opting for Rejuran Healer for comprehensive rejuvenation or Rejuran Eye for under-eye revival, this treatment delivers tangible, long-lasting results.
As K-beauty continues to innovate, Rejuran’s fusion of biotechnology and aesthetics positions it as a cornerstone of modern skincare.
Ready to Transform Your Skin? Consult a certified practitioner to explore personalized Rejuran regimens.
For product inquiries, visit trusted suppliers like Maylips or clinics listed in this guide.
References
1. SOL Aesthetics Clinic, Singapore
2. Maylips Injection Guide
3. Hale & Belle K-Beauty Trends
4. Juclinic Rejuran Overview
5. SIAN Clinic Rejuran Eye
6. Dr. Rachel Ho’s Comparison
7. Vogue K-Beauty Report
8. Westwood Clinic Guide
9. Maylips Rejuran Overview
10. SLC Clinic Comparison
This article is for informational purposes only. Consult a medical professional before undergoing any treatment.


